Welcome to the Leiden based

Brain and Development Lab

Discover our research projects:


Prosocial behaviour strongly develops during adolescence.

Leiden Consortium Individual Development (LCID)

Why are not all children equally responsive to variations in the social environment?

Self concept

Self-report is sensitive to response bias. Different components of self-concept can be reliably assessed using functional neuroimaging


Investigating developmental changes in cognitive control, impulse regulation and social-emotional functions during childhood, adolescence and emerging adulthood


Investigating self-concept, aggression regulation and vicarious reward learning in youth who have been arrested by the police before the age of twelve years.

About our Brain Lab:

The Brain and Development Lab examines fundamental changes in human brain function across childhood and adolescence.

The Leiden Brain and Development Lab, founded in 2005 by Eveline Crone, examines fundamental changes in brain function across the life span. Using longitudinal neuroimaging techniques, the lab examines developmental trajectories over time in the domains of self-development and self-regulation, social learning and prosocial behavior, as well as the predictors of contribution to society. Our motivation is to shed light on developmental processes with a particular focus on the role of social and environmental factors, such as parent and peer interactions.

With our studies, we aim to unravel the neurobiological and social factors that influence growth trajectories. Ultimately, with our research we hope to contribute to creating opportunities for youth while growing up in a complex society.

The Brain and Development lab is strongly connected to Eveline Crone’s Rotterdam lab; The Society, Youth and Neuroscience Connected (SYNC) Lab at Erasmus University Rotterdam. Within the SYNC lab, researchers study developmental neuroscience from a societal impact perspective (see www.erasmus-synclab.nl).

We also participate in the Leiden Institute for Brain and Cognition (LIBC), which is an interfaculty center for interdisciplinary research on brain and cognition at Leiden University (see www.libc-leiden.nl).

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Meet our principal investigators:

Eveline Crone

Principal Investigator

Latest publications:

Prosocial development in adolescence

Crone, E.A., & Achterberg, M. (2022). Current opinion in psychology. https://doi.org/10.1016/j.copsyc.2021.09.020


Integrating cognitive developmental neuroscience in society; Lessons learned from a multidisciplinary research project on education and social safety of Youth

Vandenbroucke, A.R.E., Crone, E.A., van Erp, J.B.F., Guroglu, B., Hulshoff Pol, H.E., de Kogel, C.H., Krabbendam, L., Jansen, L.M.C., Brouwer, A. (2021). Frontiers in Integrative Neuroscience. https://doi.org/10.3389/fnint.2021.756640



Multiple pathways of risk taking in adolescence

Crone, E.A., & van Duijvenvoorde, A.C.K. (2021). Developmental review. https://doi.org/10.1016/j.dr.2021.100996


Increased Ventromedial Prefrontal Cortex Activity in Adolescence Benefits Prosocial Reinforcement Learning

Westhoff, B., Blankenstein, N.E., Schreuders, E., Crone, E.A., & van Duijvenvoorde, A.C.K. (2021). Developmental Cognitive Neuroscience. https://doi.org/10.1016/j.dcn.2021.101018


Happy for Us not Them: Differences in neural activation in a vicarious reward task between family and strangers during adolescent development

Brandner, P., Güroğlu, B., van de Groep, S., Spaans, J.P., & Crone E.A. (2021). Developmental Cognitive Neuroscience. https://doi.org/10.1016/j.dcn.2021.100985


Mood and emotional reactivity of adolescents during the COVID-19 pandemic: short-term and long-term effects and the impact of social and socioeconomic stressors

Green, K.H., van de Groep, S., Sweijen, S.W., Becht, A.I., Buijzen, M., de Leeuw, R.N.H., Remmerswaal, D., van der Zanden, R., Engels, R.C.M.E., & Crone, E.A. (2021). Scientific Reports. https://doi.org/10.1038/s41598-021-90851-x


Overlapping and distinct neural correlates of self-evaluations and self-regulation from the perspective of self and others

Van de Groep, I.H., Bos, M.G.N., Jansen, L.M.C., Achterberg, M., Popma, A., & Crone, E.A. (2021). Neuropsychologia. https://doi.org/10.1016/j.neuropsychologia.2021.108000


Alcohol use and brain morphology in adolescence: A longitudinal study in three different cohorts

El Marroun, H., Klapwijk, E.T., Koevoets, M., Brouwer, R.M., Peters, S., Van’t Ent, D., Boomsma, D.I., Muetzel, R.L., Crone, E.A., Hulshoff Pol, H.E., & Franken, I.H.A. (2021). European Journal of Neuroschience.  https://doi.org/10.1111/ejn.15411 


The nature of the self: Neural analyses and heritability estimates of self-evaluations in middle childhood

Van Drunen, L., Dobbelaar, S., van der Cruijsen, R., van der Meulen, M., Achterberg, M., Wierenga, L.M., & Crone, E.A. (2021). Human Brain Mapping. https://doi.org/10.1002/hbm.25641